Views Read Edit View history. One striking exception to this pattern of gene distribution is the human Y chromosome. Mucignat-Caretta C ed. Role of Heterochromatin Highly differentiated Y chromosomes, such as in Drosophila melanogasterare composed largely of noncoding, highly repetitive DNA that is kept in a silenced chromatin state known as heterochromatin.
Genes Genet. Teasing apart these three mechanisms is not easy but needs to be done to understand the effect of sex chromosomes on aging. Despite these advances, it was not until Ardhendu Mukherjee and W. An added level of natural variation in gene expression is caused by allele-specific expression.
S6 Fig. The authors further suggest that other repeats may serve this function in closely related species. Insect Biochemistry and Molecular Biology.
However, M-factors identified in these species have no obvious sequence conservation, nor is their mode of function necessarily conserved. The Journal of Experimental Zoology. By submitting a comment you agree to abide by our Terms and Community Guidelines.