Site frequency spectrum. Distribution of variants across founder populations compared with three other European populations. Rare variants exploration identified previously associated genes ex: GSDMB [ 13 ], IL33 [ 15 ] and new ones ex: GRASP [ 13 ]highlighting the importance of studying their role in the context of asthma and allergy-related traits.
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Sell on Amazon Start a Selling Account. The Canadian Press Staff. Supplementary Figure 6. As founder populations are enriched with population-specific variants, we characterized the variants distribution in SLSJ and compared ex sex is the best sex in Saguenay with four European populations Finnish, Sweden, United Kingdom and Franceof which the Finnish population is another founder population.
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By Maxim Video. Supplementary Figure 1. The allergy phenotype is available for subjects, trio members, probands, parents and siblings. This approach allowed us to assess the impacts of rare and low-frequency variants in a cost-effective manner.
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